Shonda Rhimes

*Some drastic changes appear to be in the pipeline for Shonda Rhimes and her baby “Grey’s Anatomy.”

TV Guide magazine reports that Ellen Pompeo, who plays lead character Meredith Grey, said earlier this year that she wants to leave the program after two more seasons. The interview sparked rumors that Meredith’s half-sister Lexie, who is played by Chyler Leigh, will take over as the main character.

Addressing the report, Rhimes said: “It’s possible, but I don’t know that I think of it that way.”

She added that she does not know whether Pompeo will really leave.

“In my head, Meredith Grey is staying forever,” she explained. “Ellen says, ‘I have two more years and I’m going to Italy’. But I also say, ‘Two more years and I’m going to Italy’. So I will cross that bridge when I come to it.”

Rhimes continued: “For me, the show is very tied up in Meredith Grey and Cristina Yang [Sandra Oh]. If I can convince the originals we have left to stay forever, I will get down on my knees to do so.”