*It’s all over for Tyra. On Friday, she has wrapped up her talk show.

“I had journalists tell me this show was going to be canceled in two weeks, and it’s five years…”

The former model turned talk show host showed clips of memorable shows: Tyra as a fat woman, Tyra homeless, Tyra in jail — and snippets of interviews with President Obama, Hillary Clinton and John Edwards.

Larry King and others offered taped send-offs. Larry called her the ‘fiercest host’ in television. Even the queen of daytime, the Big O, Oprah Winfrey sent a recorded message saying she can’t wait to see what Tyra has in store for her next act.

Watch a report from E! News: