*“Glee,” America’s new favorite dramedy series has taken over Jay-Z’s “Empire State of Mind.” The FOX show has actually covered a few tracks, which are available via iTunes and Sirius XM Radio.

The new season of the show will follow the William McKinley High School’s harmonious ensemble as they journey to Nationals in New York City, thus making the Jay-Z/Alicia Keys duet an appropriate selection.

Other tunes that will appear in the Sept. 21 premiere include Lady Gaga and Beyonce’s “Telephone” and Poison’s “Every Rose Has Its Thorn.” Tune in at 8 pm ET.

Check out “Empire State of Mind” by “Glee”: