President Barack Obama and first lady Michelle Obama are pictured with Oprah Winfrey during a taping of The Oprah Winfrey Show at Harpo Studios in Chicago, Wednesday, April 27, 2011.

*Shortly after his birth certificate speech, President Barack Obama and first lady Michelle Obama were on Air Force One headed back to their Chicago hometown to film an episode of “The Oprah Winfrey Show.”

The first couple’s appearance is scheduled to air on Monday (May 2) as one of the final episodes of the talk show which is scheduled to end on May 25 after 25 years.

The Obamas took turns answering Winfrey’s questions during the taped interview at her studio, her first ever with a sitting president and first lady.

“Her show is coming to a conclusion of a terrific run,” White House spokesman Jay Carney said. Obama “considers Oprah a friend and he looks forward to being on the show.”