oprah & 50 cent*On the next edition of “Oprah’s Next Chapter,” the TV maven continues her chat with her once nemesis rapper/actor 50 Cent.

She asked Fiddy to name the people he knows genuinely love him. Other than his grandmother and his son, it was a question that stumped him.

“Short periods of time? Lots of people,” he said. But that’s not true love. That’s perhaps opportunistic love.”

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Lady O then hit an even bigger block when she asked him who he was certain had his back. In a pinch 50 Cent doesn’t feel that there’s anyone he can definitely count on no matter what.

“I have asked myself this question,” Winfrey said of the love query. “It’s not a very long list.” It painted a surprising picture of loneliness amidst such fame and adoration.

“Oprah’s Next Chapter” airs Sundays at 8pm E/P on OWN.