Actor Don Cheadle attends the Broadcast Television Journalists Association Second Annual Critics’ Choice Awards at The Beverly Hilton Hotel on June 18, 2012 in Beverly Hills, California.

*With memorable performances in such dramas as “Crash,” “Hotel Rwanda” and “Talk to Me” on his resume, Don Cheadle has become one of Hollywood’s most bankable dramatic actors.

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But the 47-year-old Kansas City native says comedy is actually his first love, and he’s thrilled to get a chance to flex those muscles in his Showtime series “House of Lies,” which was picked up for a second season in February.

Below, Cheadle says his whole family is funny, which inspired him to start out his career as a standup comic before making the transition to acting.

Cheadle will next be seen in the Denzel Washington film “Flight,” opening Nov. 2, 2012. Watch the trailer below.