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(L-R) Bradley Cooper, Zach Galifianakis and Ed Helmes in “The Hangover Part III”

*The third and final film in the “Hangover” franchise will arrive in theaters this month looking a bit different from its predecessors.

The Wolfpack is back – Phil (Bradley Cooper), Alan (Zach Galifianakis), Stu (Ed Helms) and Doug (Justin Bartha). But this time, they’re not spending the whole movie trying to figure out how they managed to lose a human being following a night of wild partying.

Part III finds the Wolfpack concerned with Alan’s mental state. His father has died, he’s off his meds and his friends and family are seen in the trailer trying to get him to go to treatment.

Despite the format change, there are some familiar aspects to the film. Heather Graham from Part I returns as heart-of-gold stripper Jade, Ken Jeong is back as a “darker than ever” Mr. Chow, per writer/director Todd Phillips, and a ‘Hangover” wouldn’t be a “Hangover” without Mike Tyson – who made memorable cameos in the first two films. (He admitted he was high on cocaine while filming Part I.)

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How the former heavyweight champion of the world factors in to the third film is being kept under wraps. (He’s not in any of the trailers.) But ,during interviews for the movie, Cooper did reveal that Part III as a whole – though it’s different in format from I and II – is more similar in tone to the 2009 original, and not the frenetic chaos of its Bangkok-set sequel.

“The Hangover Part III” opens in theaters on May 24. Watch the trailers below.