mario(2010-headshot-med-big)*It’s been five years since R&B’s disappearing act Mario has dropped an album.

But he’s back and ready to breathe new life into the genre, the singer says.

Mario’s new single, “Somebody Else,” features hip-hop enigma Nicki Minaj.

He accompanied the release of the record with a personal note to fans.

“Nothing can explain the excitement in my heart at this point & time in my life. I have changed so much as a man, artist, & creator, and I realize more and more everyday that it’s not about me. It’s about me doing what GOD wants me to do; change the world with my GIFT.”

“Somebody Else,” produced by Polow Da Don, is scheduled to hit iTunes on Tuesday, May 21.

“I hope this new song breathes new life into R&B and where I’m gonna take it!” Mario, 26, wrote in a handwritten note.