Serena Williams of United States of America looks dejected during her Ladies' Singles fourth round match against Sabine Lisicki of Germany on day seven of the Wimbledon Lawn Tennis Championships at the All England Lawn Tennis and Croquet Club on July 1, 2013 in London, England

Serena Williams during her Ladies’ Singles fourth round match against Sabine Lisicki of Germany on day seven of the Wimbledon Lawn Tennis Championships at the All England Lawn Tennis and Croquet Club on July 1, 2013 in London, England

*Serena Williams’ Grand Slam winning streak is over.

The world No. 1 and Wimbledon defending champion was beaten in the fourth round Monday by Sabine Lisicki 6-2, 1-6, 6-4.

Lisicki jumped on Williams early, survived a nine-game drought in the middle, then came back from a break down in the third set twice on her way to a victory.

Williams had won 34 consecutive matches before running into the big-serving German, who matched Williams’ power and took advantage of Serena’s mistakes.

Sloane Stephens of the United States returns to Monica Puig of Puerto Rico during their Women's singles match at the All England Lawn Tennis Championships in Wimbledon, London, Monday, July 1, 2013

Sloane Stephens of the United States returns to Monica Puig of Puerto Rico during their Women’s singles match at the All England Lawn Tennis Championships in Wimbledon, London, Monday, July 1, 2013

Shortly after Serena’s match, Sloane Stephens of the U.S. became the last American singles player left in the grass-court tournament by beating 19-year-old Monica Puig of Puerto Rico 4-6, 7-5, 6-1.

For the first time in 101 years, no men representing the U.S. even made it to Wimbledon’s third round.

The 17th-seeded Stephens reached her second Grand Slam quarterfinal of the year. The 20-year-old eliminated Serena in the quarterfinals at the Australian Open in January to reach her first career major semifinal.

Next for Stephens in her second appearance at Wimbledon is a match against No. 15 Marion Bartoli, the 2007 runner-up, or 104th-ranked Karin Knapp.