lupita nyongo (at naacp image awards)

*The biggest night in Hollywood is quickly approaching!

And critics and movie buffs alike are citing their last-minute Oscar predictions in the major categories.

One of the more interesting races is Best Supporting Actress. Lupita Nyong’o is the clear frontrunner, but Jennifer Lawrence is right behind her in a two-way race.

On Nyong’o’s side is the fact that Lawrence won Best (LEAD) Actress last year for her critically-acclaimed performance in “Silver Linings Playbook” — working against her somewhat.

Also, 2013 was a major year for Nyong’o as last year’s breakout star, which would make a compelling Oscar win story.

Thirdly, her performance in “12 Years a Slave” was THAT compelling and moving, and she’s been called the emotional centerpiece of the instant classic and Best Picture hopeful.

Speaking of which, “12 Years a Slave” is competing in a THREE-way race with “Gravity” and “American Hustle” for the top movie honor.

For Best Actor, Matthew McConaughey is the frontrunner for playing a homophobic AIDS patient in “Dallas Buyers Club” — while Jared Leto as a trans woman with AIDS in the same film and Cate Blanchett in Woody Allen’s “Blue Jasmine” are Best Supporting Actor and Best Actress frontrunners, respectively.

Check out Wynn Las Vegas oddsmaker John Avello Oscar odds for the major categories below (although, gambling on Oscar bets is illegal, it’s just for fun).

Best Picture

“12 Years a Slave” – 2 to 5

“American Hustle” – 4 to 1

“Gravity” – 5 to 1

“Dallas Buyers Club” – 15 to 1

“The Wolf of Wall Street” – 30 to 1

“Captain Phillips” – 50 to 1

“Philomena” – 75 to 1

“Nebraska” – 85 to 1

“Her” – 150 to 1

Best Actor

Matthew McConaughey – 1 to 2

Chiwetel Ejiofor – 4 to 1

Leonardo DiCaprio – 5 to 1

Bruce Dern – 25 to 1

Christian Bale – 30 to 1

Best Actress

Cate Blanchett – 1 to 5

Sandra Bullock – 10 to 1

Meryl Streep – 14 to 1

Amy Adams – 18 to 1

Judi Dench – 25 to 1

Best Supporting Actor

Jared Leto – 1 to 4

Michael Fassbender – 5 to 1

Barkhad Abdi – 15 to 1

Jonah Hill – 25 to 1

Bradley Cooper – 30 to 1

Best Supporting Actress

Lupita Nyong’o – 4 to 5

Jennifer Lawrence – 8 to 5

June Squibb – 15 to 1

Julia Roberts – 20 to 1

Sally Hawkins – 25 to 1