*(Via TechTimes) – People respond differently to drugs. Some individuals, for instance, experience improvement in health much faster than others who take the same medication and it appears that this holds true even with the diabetes drug Metformin.
Metformin is often prescribed as a first-line treatment for type 2 diabetes patients but the clinical trials from which the drug’s standard of care was based on were made up mostly of white participants, said Keoki Williams, from the Henry Ford Health System (HFHS) in Michigan.
Because little is known about the effects of the drug in African American diabetic patients, Williams and his colleagues conducted a study to assess the efficacy of metformin on the black population and to determine if the effect of metformin varies by race-ethnicity.
For their study published in the Journal of Clinical Endocrinology & Metabolism (JCEM) on June 12, the researchers looked at the pharmacy and medical records of more than 7,400 African American and over 8,700 white diabetic patients who took metformin to examine the participants’ exposure to the medication and other diabetes drugs. The participant of the study also had a minimum of two fills of metformin and had their hemoglobin A1c, or HbA1c, blood sugar level measured at least twice with four months interval.
This story continues at TechTimes.